$199.99
FREE Returns
FREE delivery May 19 - 20
Or fastest delivery May 15 - 16
Available to ship in 1-2 days
$$199.99 () Includes selected options. Includes initial monthly payment and selected options. Details
Price
Subtotal
$$199.99
Subtotal
Initial payment breakdown
Shipping cost, delivery date, and order total (including tax) shown at checkout.
Ships from
Amazon.com
Ships from
Amazon.com
Sold by
Amazon.com
Sold by
Amazon.com
Returns
Eligible for Return, Refund or Replacement within 30 days of receipt
Eligible for Return, Refund or Replacement within 30 days of receipt
This item can be returned in its original condition for a full refund or replacement within 30 days of receipt.
Read full return policy
Returns
Eligible for Return, Refund or Replacement within 30 days of receipt
This item can be returned in its original condition for a full refund or replacement within 30 days of receipt.
Read full return policy
Payment
Secure transaction
Your transaction is secure
We work hard to protect your security and privacy. Our payment security system encrypts your information during transmission. We don’t share your credit card details with third-party sellers, and we don’t sell your information to others. Learn more
Payment
Secure transaction
We work hard to protect your security and privacy. Our payment security system encrypts your information during transmission. We don’t share your credit card details with third-party sellers, and we don’t sell your information to others. Learn more
Amazon book clubs early access
Loading your book clubs
There was a problem loading your book clubs. Please try again.
Not in a club? Learn more
Amazon book clubs early access

Join or create book clubs

Choose books together

Track your books
Bring your club to Amazon Book Clubs, start a new book club and invite your friends to join, or find a club that’s right for you for free.
Explore Amazon Book Clubs
Kindle app logo image

Download the free Kindle app and start reading Kindle books instantly on your smartphone, tablet, or computer - no Kindle device required.

Read instantly on your browser with Kindle for Web.

Using your mobile phone camera - scan the code below and download the Kindle app.

QR code to download the Kindle App

Evolution, Biodiversity and a Reassessment of the Hygiene Hypothesis (Progress in Inflammation Research, 89) 1st ed. 2022 Edition

by Graham A. W. Rook (Editor), Christopher A. Lowry (Editor)
See all formats and editions
{"desktop_buybox_group_1":[{"displayPrice":"$199.99","priceAmount":199.99,"currencySymbol":"$","integerValue":"199","decimalSeparator":".","fractionalValue":"99","symbolPosition":"left","hasSpace":false,"showFractionalPartIfEmpty":true,"offerListingId":"Brqtbm9M6Ng8CFjiigO8CrHmot0d96hICsMrB3DYl4V%2BtASeIUx2E40hluALxXsb4GFnRC4PvQ0QAVXiHKtyOK9ptFmfGOdi78Yk0rue%2FpbmX0FUfUklSO5aGoc1OOgW3H%2FuLU7KMkyytKn2rYS9mA%3D%3D","locale":"en-US","buyingOptionType":"NEW","aapiBuyingOptionIndex":0}]}

Purchase options and add-ons

This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the “hygiene hypothesis” by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation.

Read more Read less
Previous page
  1. ISBN-10
    3030910504
  2. ISBN-13
    978-3030910501
  3. Edition
    1st ed. 2022
  4. Publisher
    Springer
  5. Publication date
    March 25, 2022
  6. Language
    English
  7. Dimensions
    6.3 x 0.95 x 9.5 inches
  8. Print length
    424 pages
  9. See all details
Next page
Amazon First Reads | Editors' picks at exclusive prices

Editorial Reviews

From the Back Cover

This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the “hygiene hypothesis” by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation.

About the Author

Graham A. W. Rook, BA MB BChir MD, is emeritus Professor of Medical Microbiology at UCL (University College London). He was educated at the University of Cambridge and at St. Thomas’ Hospital London. He became professor of medical microbiology at UCL in 1994. The theme of his research was initially the immunopathology of tuberculosis, but in recent years GR’s focus has been the application of a Darwinian perspective to the effects on health of diminishing exposure to microorganisms from the natural environment, and of the changing composition of our commensal microbiota. GR coined the expression “Old Friends Hypothesis” to highlight a Darwinian re-interpretation of the hygiene hypothesis in 2003. Recently, in collaboration with neuroscientists and psychiatrists, this thinking has been applied to psychiatric disorders that are accompanied by persistently raised biomarkers of inflammation and to the reduced stress resilience of people living in high-income countries. Thus GR’s approach is interdisciplinary, with emphasis on integrative physiology.

Christopher A. Lowry, Ph.D. is an Associate Professor in the Department of Integrative Physiology, Center for Neuroscience, and Center for Microbial Exploration at the University of Colorado Boulder, with a secondary appointment in the Department of Physical Medicine and Rehabilitation (PM&R) and Center for Neuroscience, University of Colorado Anschutz Medical Campus, a Principal Investigator in the Department of Veterans Affairs Eastern Colorado Health Care System, VA Rocky Mountain Mental Illness Research, Education, & Clinical Center (MIRECC), director of the Behavioral Neuroendocrinology Laboratory at CU Boulder, Co-Director of the Military and Veteran Microbiome Consortium for Research and Education (MVM-CoRE), Senior Fellow and member of the Board of Directors of inVIVO Planetary Health, of the Worldwide Universities Network (WUN), and a member of the Board of Directors of Trails Please Foundation. Dr. Lowry’s research program focuses on understanding stress-related physiology and behavior with an emphasis on the microbiome-gut-brain axis.

Product details

  • Publisher ‏ : ‎ Springer; 1st ed. 2022 edition (March 25, 2022)
  • Language ‏ : ‎ English
  • Hardcover ‏ : ‎ 424 pages
  • ISBN-10 ‏ : ‎ 3030910504
  • ISBN-13 ‏ : ‎ 978-3030910501
  • Item Weight ‏ : ‎ 1.86 pounds
  • Dimensions ‏ : ‎ 6.3 x 0.95 x 9.5 inches

Customer reviews

No customer reviews